STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RASGRP1Ras-GEF domain-containing protein. (158 aa)    
Predicted Functional Partners:
RAP1B
RAP1B, member of RAS oncogene family.
    
 0.975
RRAS2
RAS related 2.
    
 0.961
RASGRP3
RAS guanyl releasing protein 3.
  
  
 
0.951
MRAS
Muscle RAS oncogene homolog.
    
 0.949
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
     
 0.930
PLCG1
Uncharacterized protein.
    
 0.930
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2.
     
 0.913
F6PLS0_ORNAN
Uncharacterized protein.
   
 0.716
F6T865_ORNAN
Uncharacterized protein.
    
 0.685
F6SHH1_ORNAN
Uncharacterized protein.
    
 0.675
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.