STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCZ1Uncharacterized protein. (125 aa)    
Predicted Functional Partners:
PLCB4
Phosphoinositide phospholipase C.
   
 
 0.937
PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 
 0.930
PLCB3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 
 0.929
PLCB2
PH_14 domain-containing protein.
   
 
 0.927
PLCG1
Uncharacterized protein.
     
 0.918
PLCG2
SH2 domain-containing protein.
     
 0.918
PLCE1
Phosphoinositide phospholipase C.
     
  0.915
IPMK
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.910
ITPR1
Uncharacterized protein.
   
 
 0.907
PLCD4
PI-PLC Y-box domain-containing protein.
   
  0.907
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.