STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEK04239.1RNA polymerase, sigma 54 subunit, RpoN/SigL. (514 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.977
SEK15651.1
DNA-directed RNA polymerase subunit beta'.
  
 
 
 0.976
SEK15653.1
DNA-directed RNA polymerase subunit beta.
    
 
 0.972
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.961
SEJ02653.1
RNA polymerase, sigma 54 subunit, RpoN/SigL; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 
0.916
SEK10705.1
Transcriptional regulator, propionate catabolism operon regulatory protein.
 
  
 0.895
SEJ65799.1
Signal peptidase I; Belongs to the peptidase S26 family.
  
  
 0.884
SEJ83243.1
PAS/PAC sensor hybrid histidine kinase.
    
 0.881
SEK08085.1
His Kinase A (phospho-acceptor) domain-containing protein.
    
 0.878
ntrC
Nitrogen metabolism transcriptional regulator, NtrC, Fis family; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
 
  
 0.853
Your Current Organism:
Paraburkholderia tropica
NCBI taxonomy Id: 92647
Other names: ATCC BAA-831, Burkholderia tropica, Burkholderia tropica Reis et al. 2004, DSM 15359, LMG 22274, LMG:22274, P. tropica, Paraburkholderia tropica (Reis et al. 2004) Sawana et al. 2015, strain Ppe8
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