STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BAM01743.1Putative TPP binding protein; Belongs to the TPP enzyme family. (581 aa)    
Predicted Functional Partners:
ilvN
Acetolactate synthase small subunit.
 
 0.949
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.890
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.719
BAM01190.1
Hypothetical protein.
  
    0.702
BAL98109.1
Putative threonine dehydratase.
  
 0.643
BAL98573.1
Putative threonine dehydratase.
  
 0.643
BAM01863.1
Putative threonine dehydratase.
  
 0.643
maeB
NADP-dependent malic enzyme.
  
  
 0.579
BAM00841.1
Hypothetical protein.
  
    0.564
gltB
Glutamate synthase large subunit.
  
  
 0.562
Your Current Organism:
Caldilinea aerophila
NCBI taxonomy Id: 926550
Other names: C. aerophila DSM 14535 = NBRC 104270, Caldilinea aerophila DSM 14535, Caldilinea aerophila DSM 14535 = NBRC 104270, Caldilinea aerophila NBRC 104270, Caldilinea aerophila NBRC 104270 = DSM 14535, Caldilinea aerophila STL-6-O1
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