node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EIJ38020.1 | EIJ38021.1 | JoomaDRAFT_0999 | JoomaDRAFT_1000 | Metalloendopeptidase-like membrane protein; PFAM: Peptidase family M23. | PFAM: Tryptophan 2,3-dioxygenase. | 0.773 |
EIJ38020.1 | EIJ38022.1 | JoomaDRAFT_0999 | JoomaDRAFT_1001 | Metalloendopeptidase-like membrane protein; PFAM: Peptidase family M23. | PFAM: Protein of unknown function (DUF3108). | 0.773 |
EIJ38020.1 | pgi | JoomaDRAFT_0999 | JoomaDRAFT_0998 | Metalloendopeptidase-like membrane protein; PFAM: Peptidase family M23. | PFAM: Phosphoglucose isomerase; Belongs to the GPI family. | 0.774 |
EIJ38021.1 | EIJ38020.1 | JoomaDRAFT_1000 | JoomaDRAFT_0999 | PFAM: Tryptophan 2,3-dioxygenase. | Metalloendopeptidase-like membrane protein; PFAM: Peptidase family M23. | 0.773 |
EIJ38021.1 | EIJ38022.1 | JoomaDRAFT_1000 | JoomaDRAFT_1001 | PFAM: Tryptophan 2,3-dioxygenase. | PFAM: Protein of unknown function (DUF3108). | 0.875 |
EIJ38021.1 | EIJ38279.1 | JoomaDRAFT_1000 | JoomaDRAFT_1263 | PFAM: Tryptophan 2,3-dioxygenase. | Putative metal-dependent hydrolase; PFAM: Putative cyclase. | 0.984 |
EIJ38021.1 | EIJ38346.1 | JoomaDRAFT_1000 | JoomaDRAFT_1330 | PFAM: Tryptophan 2,3-dioxygenase. | Esterase/lipase; PFAM: alpha/beta hydrolase fold. | 0.827 |
EIJ38021.1 | EIJ40434.1 | JoomaDRAFT_1000 | JoomaDRAFT_3493 | PFAM: Tryptophan 2,3-dioxygenase. | MAF protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.766 |
EIJ38021.1 | kmo | JoomaDRAFT_1000 | JoomaDRAFT_1910 | PFAM: Tryptophan 2,3-dioxygenase. | 2-polyprenyl-6-methoxyphenol hydroxylase-like oxidoreductase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.805 |
EIJ38021.1 | kynU | JoomaDRAFT_1000 | JoomaDRAFT_1903 | PFAM: Tryptophan 2,3-dioxygenase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.991 |
EIJ38021.1 | nbaC | JoomaDRAFT_1000 | JoomaDRAFT_1510 | PFAM: Tryptophan 2,3-dioxygenase. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.688 |
EIJ38021.1 | pgi | JoomaDRAFT_1000 | JoomaDRAFT_0998 | PFAM: Tryptophan 2,3-dioxygenase. | PFAM: Phosphoglucose isomerase; Belongs to the GPI family. | 0.816 |
EIJ38021.1 | trpA | JoomaDRAFT_1000 | JoomaDRAFT_2740 | PFAM: Tryptophan 2,3-dioxygenase. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.884 |
EIJ38022.1 | EIJ38020.1 | JoomaDRAFT_1001 | JoomaDRAFT_0999 | PFAM: Protein of unknown function (DUF3108). | Metalloendopeptidase-like membrane protein; PFAM: Peptidase family M23. | 0.773 |
EIJ38022.1 | EIJ38021.1 | JoomaDRAFT_1001 | JoomaDRAFT_1000 | PFAM: Protein of unknown function (DUF3108). | PFAM: Tryptophan 2,3-dioxygenase. | 0.875 |
EIJ38022.1 | pgi | JoomaDRAFT_1001 | JoomaDRAFT_0998 | PFAM: Protein of unknown function (DUF3108). | PFAM: Phosphoglucose isomerase; Belongs to the GPI family. | 0.818 |
EIJ38279.1 | EIJ38021.1 | JoomaDRAFT_1263 | JoomaDRAFT_1000 | Putative metal-dependent hydrolase; PFAM: Putative cyclase. | PFAM: Tryptophan 2,3-dioxygenase. | 0.984 |
EIJ38279.1 | kmo | JoomaDRAFT_1263 | JoomaDRAFT_1910 | Putative metal-dependent hydrolase; PFAM: Putative cyclase. | 2-polyprenyl-6-methoxyphenol hydroxylase-like oxidoreductase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.962 |
EIJ38279.1 | kynU | JoomaDRAFT_1263 | JoomaDRAFT_1903 | Putative metal-dependent hydrolase; PFAM: Putative cyclase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.991 |
EIJ38279.1 | nbaC | JoomaDRAFT_1263 | JoomaDRAFT_1510 | Putative metal-dependent hydrolase; PFAM: Putative cyclase. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.575 |