STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menD2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (536 aa)    
Predicted Functional Partners:
AEV31327.1
PFAM: chorismate binding enzyme; TIGRFAM: isochorismate synthases.
 
 0.987
menB
Dihydroxynaphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
  
 0.890
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
   
 0.832
AEV31354.1
Enolase superfamily enzyme related to L-alanine-DL-glutamate epimerase; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; TIGRFAM: o-succinylbenzoate synthase.
 
   
 0.827
AEV31355.1
acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; PFAM: AMP-binding enzyme.
 
  
 0.820
AEV31330.1
Hypothetical protein; PFAM: Bacterial membrane flanked domain.
       0.773
AEV31331.1
Putative membrane protein; PFAM: Bacterial membrane flanked domain.
       0.773
AEV31326.1
Hypothetical protein; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1.
 
   
 0.714
AEV31332.1
Hypothetical protein.
       0.515
AEV33232.1
enoyl-CoA hydratase/carnithine racemase; PFAM: Enoyl-CoA hydratase/isomerase family; TIGRFAM: phenylacetate degradation probable enoyl-CoA hydratase paaB; Belongs to the enoyl-CoA hydratase/isomerase family.
 
   
 0.401
Your Current Organism:
Owenweeksia hongkongensis
NCBI taxonomy Id: 926562
Other names: Cryomorphaceae bacterium UST20020801, O. hongkongensis DSM 17368, Owenweeksia hongkongensis DSM 17368, Owenweeksia hongkongensis UST20020801
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