STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIC14516.1Chromosome segregation protein SMC. (1184 aa)    
Predicted Functional Partners:
AIC14908.1
Putative chromosome segregation and condensation protein ScpA.
  
 
 0.969
AIC14907.1
Hypothetical protein.
 
 
 0.880
AIC15933.1
Putative DNA double-strand break repair Rad50 ATPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.702
AIC16446.1
Putative histone deacetylase superfamily (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
 0.685
srp54
Signal recognition particle SRP54 subunit protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
   0.654
topA
DNA topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...]
  
 
 0.627
AIC15151.1
ParB-like nuclease domain-containing protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.599
AIC16316.1
Putative molybdopterin biosynthesis protein MoeB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.593
ftsZ
Cell division protein FtsZ; Function of strongly homologous gene; cell process.
 
  
 0.585
ino
Myo-inositol-1-phosphate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
   
   0.575
Your Current Organism:
Nitrososphaera viennensis
NCBI taxonomy Id: 926571
Other names: Candidatus Nitrososphaera sp. EN76, N. viennensis EN76, Nitrososphaera viennensis EN76, Nitrososphaera viennensis str. EN76, Nitrososphaera viennensis strain EN76
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