STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gapPutative glyceraldehyde-3-phosphate dehydrogenase, phosphorylating; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (379 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Function of strongly homologous gene; enzyme; Belongs to the triosephosphate isomerase family.
 
 0.999
pgk
Phosphoglycerate kinase; Function of strongly homologous gene; enzyme; Belongs to the phosphoglycerate kinase family.
  
 
 0.992
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.991
fbp
Bifunctional fructose-1,6-bisphosphatase; Function of strongly homologous gene; enzyme.
 
 
 0.957
tktA
Ribulose-phosphate 3-epimerase protein with N-terminal transketolase domain; Function of strongly homologous gene; enzyme.
  
 
 0.951
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.930
aroGFH
Putative 3-deoxy-7-phosphoheptulonate synthase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
    
 0.922
rpl4p
50S ribosomal protein L4p; Function of strongly homologous gene; structure.
  
 
 0.919
mdh
Malate dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the LDH/MDH superfamily.
  
 
 0.907
tktB
Transketolase, C-terminal subunit; Function of strongly homologous gene; enzyme.
    
 0.863
Your Current Organism:
Nitrososphaera viennensis
NCBI taxonomy Id: 926571
Other names: Candidatus Nitrososphaera sp. EN76, N. viennensis EN76, Nitrososphaera viennensis EN76, Nitrososphaera viennensis str. EN76, Nitrososphaera viennensis strain EN76
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