STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cofGFO synthase subunit 1; Function of strongly homologous gene; enzyme. (391 aa)    
Predicted Functional Partners:
cofH1
FO synthase subunit 2; Function of strongly homologous gene; enzyme.
  
 0.999
cofD
LPPG:FO 2-phospho-L-lactate transferase; Function of strongly homologous gene; enzyme.
 
  
 0.976
cofH3
FO synthase subunit 2; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
   
 0.960
cofH2
FO synthase subunit 2; Function of strongly homologous gene; enzyme.
   
0.937
cofC
2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
 
   
 0.814
thiC
Phosphomethylpyrimidine synthase.
  
  
 0.724
cofE-1
F420-0:gamma-L-glutamate ligase; Function of strongly homologous gene; enzyme.
 
   
 0.719
cofE-2
F420-0:gamma-L-glutamate ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   
 0.690
AIC17027.1
Putative NADPH-dependent F420 reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
   
 0.656
AIC15361.1
Putative 2-alkenal reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.625
Your Current Organism:
Nitrososphaera viennensis
NCBI taxonomy Id: 926571
Other names: Candidatus Nitrososphaera sp. EN76, N. viennensis EN76, Nitrososphaera viennensis EN76, Nitrososphaera viennensis str. EN76, Nitrososphaera viennensis strain EN76
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