STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIC15714.1Putative chaperonin Hsp60/Cpn60/TCP-1; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; factor; Belongs to the TCP-1 chaperonin family. (524 aa)    
Predicted Functional Partners:
AIC15713.1
Hypothetical protein.
       0.773
ureF
Putative urease accessory protein UreF; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
       0.755
ureE
Putative urease accessory protein UreE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.755
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
  
 0.750
dnaK
Chaperone protein dnaK; Acts as a chaperone.
  
 
 0.746
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
       0.636
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
       0.631
tbp
TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
  
 
 0.573
aIF-2
Translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
  
 
 0.543
rps2p
30S ribosomal protein S2p; Function of strongly homologous gene; structure; Belongs to the universal ribosomal protein uS2 family.
 
 
 0.529
Your Current Organism:
Nitrososphaera viennensis
NCBI taxonomy Id: 926571
Other names: Candidatus Nitrososphaera sp. EN76, N. viennensis EN76, Nitrososphaera viennensis EN76, Nitrososphaera viennensis str. EN76, Nitrososphaera viennensis strain EN76
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