STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIC17051.1uroporphyrinogen-III C-methyltransferase; Function of strongly homologous gene; enzyme; Belongs to the precorrin methyltransferase family. (264 aa)    
Predicted Functional Partners:
hemD
uroporphyrinogen-III synthase.
 
 0.999
AIC14255.1
Putative siroheme synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 0.998
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.996
sir
Putative ferredoxin-dependent sulfite reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.965
cobI
Precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.
  
 
0.940
AIC15794.1
Putative cob(II)yrinic acid a,c-diamide reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.910
AIC15489.1
Putative PAPS reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.898
cobB
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
    
 0.870
cysC
Putative adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate.
  
  
 0.869
hemL2
Glutamate-1-semialdehyde 2,1-aminomutase.
     
 0.858
Your Current Organism:
Nitrososphaera viennensis
NCBI taxonomy Id: 926571
Other names: Candidatus Nitrososphaera sp. EN76, N. viennensis EN76, Nitrososphaera viennensis EN76, Nitrososphaera viennensis str. EN76, Nitrososphaera viennensis strain EN76
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