STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIP91_009698Uncharacterized protein. (464 aa)    
Predicted Functional Partners:
RFA1
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.789
EIP91_005304
Uncharacterized protein.
    
 0.789
RAD52
DNA repair protein rad52.
    
 0.718
POL30
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
  0.711
KU70
ATP-dependent DNA helicase II subunit 1.
    
 
 0.694
EIP91_002567
XPGI domain-containing protein.
    
 0.685
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
    
 0.685
EIP91_001235
Uncharacterized protein.
    
 0.685
MEC1
Serine/threonine-protein kinase M1; Belongs to the PI3/PI4-kinase family.
   
 0.680
KU80
ATP-dependent DNA helicase II subunit 2.
    
 
 0.679
Your Current Organism:
Steccherinum ochraceum
NCBI taxonomy Id: 92696
Other names: S. ochraceum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.