AKF04625.1 protein (Sandaracinus amylolyticus)

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second shell of interactors

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filled nodes:
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Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

AKF04625.1

Serine/threonine protein kinase. (699 aa)

Predicted Functional Partners:

AKF04626.1

0.598

AKF04627.1

0.598

AKF04624.1

0.537

AKF04623.1

0.477

Your Current Organism:

Sandaracinus amylolyticus

NCBI taxonomy Id: 927083
Other names: DSM 53668, NCCB 100362, S. amylolyticus, Sandaracinus amylolyticus Mohr et al. 2012, Sorangiineae bacterium NOSO 4, strain NOSO-4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKF04623.1	AKF04624.1	DB32_001772	DB32_001773	Transcriptional regulator, MerR family protein.	Hypothetical protein.	0.628
AKF04623.1	AKF04625.1	DB32_001772	DB32_001774	Transcriptional regulator, MerR family protein.	Serine/threonine protein kinase.	0.477
AKF04623.1	AKF04627.1	DB32_001772	DB32_001776	Transcriptional regulator, MerR family protein.	Hypothetical protein.	0.404
AKF04624.1	AKF04623.1	DB32_001773	DB32_001772	Hypothetical protein.	Transcriptional regulator, MerR family protein.	0.628
AKF04624.1	AKF04625.1	DB32_001773	DB32_001774	Hypothetical protein.	Serine/threonine protein kinase.	0.537
AKF04624.1	AKF04626.1	DB32_001773	DB32_001775	Hypothetical protein.	Hypothetical protein.	0.427
AKF04624.1	AKF04627.1	DB32_001773	DB32_001776	Hypothetical protein.	Hypothetical protein.	0.427
AKF04625.1	AKF04623.1	DB32_001774	DB32_001772	Serine/threonine protein kinase.	Transcriptional regulator, MerR family protein.	0.477
AKF04625.1	AKF04624.1	DB32_001774	DB32_001773	Serine/threonine protein kinase.	Hypothetical protein.	0.537
AKF04625.1	AKF04626.1	DB32_001774	DB32_001775	Serine/threonine protein kinase.	Hypothetical protein.	0.598
AKF04625.1	AKF04627.1	DB32_001774	DB32_001776	Serine/threonine protein kinase.	Hypothetical protein.	0.598
AKF04626.1	AKF04624.1	DB32_001775	DB32_001773	Hypothetical protein.	Hypothetical protein.	0.427
AKF04626.1	AKF04625.1	DB32_001775	DB32_001774	Hypothetical protein.	Serine/threonine protein kinase.	0.598
AKF04626.1	AKF04627.1	DB32_001775	DB32_001776	Hypothetical protein.	Hypothetical protein.	0.773
AKF04627.1	AKF04623.1	DB32_001776	DB32_001772	Hypothetical protein.	Transcriptional regulator, MerR family protein.	0.404
AKF04627.1	AKF04624.1	DB32_001776	DB32_001773	Hypothetical protein.	Hypothetical protein.	0.427
AKF04627.1	AKF04625.1	DB32_001776	DB32_001774	Hypothetical protein.	Serine/threonine protein kinase.	0.598
AKF04627.1	AKF04626.1	DB32_001776	DB32_001775	Hypothetical protein.	Hypothetical protein.	0.773

Network Stats

number of nodes:

11

number of edges:

46

average node degree:

8.36

avg. local clustering coefficient:

0.885

expected number of edges:

11

PPI enrichment p-value:

6.11e-15

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009152

Purine ribonucleotide biosynthetic process

8 of 35

1.73

3.53

5.03e-11

GO:0042777

Proton motive force-driven plasma membrane ATP synthesis

2 of 2

2.37

1.5

0.0016

GO:0044271

Cellular nitrogen compound biosynthetic process

9 of 276

0.89

0.92

2.30e-06

GO:1901566

Organonitrogen compound biosynthetic process

9 of 286

0.87

0.9

2.98e-06

GO:0044249

Cellular biosynthetic process

10 of 497

0.68

0.62

1.47e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046933

Proton-transporting ATP synthase activity, rotational mechanism

7 of 7

2.37

5.5

3.76e-12

GO:0046961

Proton-transporting ATPase activity, rotational mechanism

2 of 2

2.37

1.39

0.0026

GO:0035639

Purine ribonucleoside triphosphate binding

7 of 263

0.8

0.65

0.00098

GO:0032555

Purine ribonucleotide binding

7 of 263

0.8

0.65

0.00098

GO:0005524

ATP binding

6 of 236

0.78

0.58

0.0036

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045259

Proton-transporting ATP synthase complex

6 of 6

2.37

4.91

9.35e-11

GO:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

4 of 4

2.37

3.35

2.85e-07

GO:0045263

Proton-transporting ATP synthase complex, coupling factor F(o)

2 of 2

2.37

1.57

0.0012

GO:0032991

Protein-containing complex

7 of 107

1.19

1.46

1.16e-06

GO:0005886

Plasma membrane

7 of 296

0.75

0.61

0.00080

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2079

ATP synthesis

6 of 6

2.37

4.57

5.81e-10

CL:1957

Ribosome, and Ribonucleoside triphosphate biosynthetic process

7 of 67

1.39

1.94

3.34e-07

CL:1946

Mixed, incl. Translation, and ATP-dependent activity

9 of 157

1.13

1.42

2.06e-07

CL:1947

Translation, and Catalytic activity, acting on RNA

8 of 142

1.12

1.35

9.47e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00190

Oxidative phosphorylation

7 of 32

1.71

3.07

3.42e-09

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0045259

Proton-transporting ATP synthase complex

7 of 9

2.26

5.22

6.04e-12

GOCC:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

5 of 5

2.37

4.02

1.00e-08

GOCC:0045263

Proton-transporting ATP synthase complex, coupling factor F(o)

2 of 4

2.07

1.11

0.0078

GOCC:0032991

Protein-containing complex

9 of 293

0.86

6.54e-06

GOCC:0005622

Intracellular

11 of 956

0.43

0.37

0.00066

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0375

Hydrogen ion transport

6 of 6

2.37

4.79

1.81e-10

KW-0066

ATP synthesis

6 of 6

2.37

4.79

1.81e-10

KW-0139

CF(1)

4 of 4

2.37

3.21

5.52e-07

KW-1003

Cell membrane

6 of 72

1.29

1.54

7.51e-06

KW-0138

CF(0)

2 of 2

2.37

1.4

0.0025

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02874

ATP synthase alpha/beta family, beta-barrel domain

2 of 2

2.37

0.78

0.0380

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