AKF10580.1 protein (Sandaracinus amylolyticus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

AKF10580.1

Hypothetical protein. (335 aa)

Predicted Functional Partners:

AKF10581.1

0.773

AKF10582.1

0.709

AKF10206.1

0.675

AKF10204.1

0.666

AKF08175.1

0.593

AKF05893.1

0.534

AKF06392.1

0.527

AKF04925.1

0.511

AKF06548.1

0.509

AKF04674.1

0.470

Your Current Organism:

Sandaracinus amylolyticus

NCBI taxonomy Id: 927083
Other names: DSM 53668, NCCB 100362, S. amylolyticus, Sandaracinus amylolyticus Mohr et al. 2012, Sorangiineae bacterium NOSO 4, strain NOSO-4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKF04674.1	AKF10204.1	DB32_001823	DB32_007353	Hypothetical protein.	High-affnity carbon uptake protein Hat/HatR.	0.448
AKF04674.1	AKF10206.1	DB32_001823	DB32_007355	Hypothetical protein.	High-affnity carbon uptake protein Hat/HatR.	0.537
AKF04674.1	AKF10580.1	DB32_001823	DB32_007729	Hypothetical protein.	Hypothetical protein.	0.470
AKF04925.1	AKF10580.1	DB32_002074	DB32_007729	Hypothetical protein; Hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives.	Hypothetical protein.	0.511
AKF05893.1	AKF10580.1	DB32_003042	DB32_007729	Putative secreted esterase.	Hypothetical protein.	0.534
AKF06392.1	AKF10580.1	DB32_003541	DB32_007729	ABC transporter, ATP-binding/permease protein.	Hypothetical protein.	0.527
AKF06548.1	AKF10580.1	DB32_003697	DB32_007729	ATP-binding protein of ABC transporter.	Hypothetical protein.	0.509
AKF08175.1	AKF10580.1	DB32_005324	DB32_007729	Hypothetical protein.	Hypothetical protein.	0.593
AKF10204.1	AKF04674.1	DB32_007353	DB32_001823	High-affnity carbon uptake protein Hat/HatR.	Hypothetical protein.	0.448
AKF10204.1	AKF10206.1	DB32_007353	DB32_007355	High-affnity carbon uptake protein Hat/HatR.	High-affnity carbon uptake protein Hat/HatR.	0.473
AKF10204.1	AKF10580.1	DB32_007353	DB32_007729	High-affnity carbon uptake protein Hat/HatR.	Hypothetical protein.	0.666
AKF10206.1	AKF04674.1	DB32_007355	DB32_001823	High-affnity carbon uptake protein Hat/HatR.	Hypothetical protein.	0.537
AKF10206.1	AKF10204.1	DB32_007355	DB32_007353	High-affnity carbon uptake protein Hat/HatR.	High-affnity carbon uptake protein Hat/HatR.	0.473
AKF10206.1	AKF10580.1	DB32_007355	DB32_007729	High-affnity carbon uptake protein Hat/HatR.	Hypothetical protein.	0.675
AKF10580.1	AKF04674.1	DB32_007729	DB32_001823	Hypothetical protein.	Hypothetical protein.	0.470
AKF10580.1	AKF04925.1	DB32_007729	DB32_002074	Hypothetical protein.	Hypothetical protein; Hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives.	0.511
AKF10580.1	AKF05893.1	DB32_007729	DB32_003042	Hypothetical protein.	Putative secreted esterase.	0.534
AKF10580.1	AKF06392.1	DB32_007729	DB32_003541	Hypothetical protein.	ABC transporter, ATP-binding/permease protein.	0.527
AKF10580.1	AKF06548.1	DB32_007729	DB32_003697	Hypothetical protein.	ATP-binding protein of ABC transporter.	0.509
AKF10580.1	AKF08175.1	DB32_007729	DB32_005324	Hypothetical protein.	Hypothetical protein.	0.593

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

27

PPI enrichment p-value:

1.05e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 104

1.5

3.1

6.57e-14

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019843

rRNA binding

10 of 40

1.87

5.09

5.87e-16

GO:0003735

Structural constituent of ribosome

11 of 51

1.81

5.01

2.68e-17

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 57

1.76

4.78

1.76e-17

GO:0044391

Ribosomal subunit

4 of 12

2.0

2.62

2.79e-06

GO:0015934

Large ribosomal subunit

3 of 6

2.17

2.24

4.01e-05

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:34833134

(2021) Genome-Wide Investigation and Analysis of Microsatellites and Compound Microsatellites in Leptolyngbya-like Species, Cyanobacteria.

6 of 15

2.08

4.05

8.68e-10

PMID:32977771

(2020) Role of diversity-generating retroelements for regulatory pathway tuning in cyanobacteria.

2 of 2

2.47

1.47

0.0019

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:151

rRNA-binding

10 of 13

2.36

8.32

1.13e-19

CL:149

rRNA-binding

11 of 21

2.19

7.89

7.79e-21

CL:152

Mixed, incl. Large ribosomal subunit, and K Homology domain, type 2

6 of 7

2.41

5.29

1.63e-11

CL:165

KOW (Kyprides, Ouzounis, Woese) motif., and rRNA-binding

4 of 6

2.3

3.19

4.89e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

cgc03010

Ribosome

11 of 53

1.79

5.02

6.52e-18

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

8 of 39

1.79

3.73

3.88e-11

GOCC:0044391

Ribosomal subunit

6 of 19

1.97

3.67

2.96e-09

GOCC:0022626

Cytosolic ribosome

4 of 16

1.87

2.28

1.04e-05

GOCC:0015934

Large ribosomal subunit

3 of 6

2.17

2.13

6.70e-05

GOCC:0022627

Cytosolic small ribosomal subunit

3 of 13

1.84

1.65

0.00036

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0699

rRNA-binding

10 of 39

1.88

5.26

1.55e-16

KW-0689

Ribosomal protein

11 of 57

1.76

4.76

2.68e-17

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