STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKF11562.1Hypothetical protein. (316 aa)    
Predicted Functional Partners:
AKF11563.1
RNA polymerase sigma factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily.
       0.631
AKF07337.1
Hypothetical protein.
   
    0.587
AKF05503.1
Trp repressor binding protein; Belongs to the WrbA family.
   
  
 0.584
AKF11561.1
Phosphonate ABC transporter phosphate-binding periplasmic component.
       0.531
AKF11560.1
Alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family.
       0.518
AKF04420.1
Alpha,alpha-trehalose-phosphate synthase.
   
    0.499
AKF06555.1
Alpha,alpha-trehalose-phosphate synthase.
   
    0.499
AKF08771.1
Alpha,alpha-trehalose-phosphate synthase.
   
    0.499
AKF06647.1
Topoisomerase IV subunit A.
  
    0.416
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
    0.416
Your Current Organism:
Sandaracinus amylolyticus
NCBI taxonomy Id: 927083
Other names: DSM 53668, NCCB 100362, S. amylolyticus, Sandaracinus amylolyticus Mohr et al. 2012, Sorangiineae bacterium NOSO 4, strain NOSO-4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.