STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFB76234.1Oxygen-dependent protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (451 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.991
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
 
 0.986
SFC06282.1
Coproporphyrinogen oxidase.
  
 
 0.883
SFC68104.1
Oxygen-independent coproporphyrinogen-3 oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
    
 0.879
SFC39435.1
Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
    
 0.571
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
     
 0.562
SFB76210.1
Outer membrane protein W.
       0.496
SFC05894.1
Phytoene/squalene synthetase.
     
 0.495
SFC74102.1
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
    
  0.458
SFC14708.1
UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
    
  0.457
Your Current Organism:
Flexibacter flexilis
NCBI taxonomy Id: 927664
Other names: F. flexilis DSM 6793, Flexibacter flexilis ATCC 23079, Flexibacter flexilis DSM 6793, Flexibacter flexilis IFO 15060, Flexibacter flexilis str. DSM 6793, Flexibacter flexilis strain DSM 6793
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