SFC02672.1 protein (Flexibacter flexilis) - STRING interaction network

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

SFC02672.1

Por secretion system C-terminal sorting domain-containing protein. (420 aa)

Predicted Functional Partners:

SFB83787.1

0.761

SFC26541.1

0.754

SFC42881.1

0.728

SFC37454.1

0.711

SFB71898.1

0.710

SFC49257.1

0.697

SFB84923.1

0.687

SFC17565.1

0.683

SFC26610.1

0.661

SFB95717.1

0.640

Your Current Organism:

Flexibacter flexilis

NCBI taxonomy Id: 927664
Other names: F. flexilis DSM 6793, Flexibacter flexilis ATCC 23079, Flexibacter flexilis DSM 6793, Flexibacter flexilis IFO 15060, Flexibacter flexilis str. DSM 6793, Flexibacter flexilis strain DSM 6793

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFB71898.1	SFB83787.1	SAMN05421780_10182	SAMN05421780_101702	Por secretion system C-terminal sorting domain-containing protein.	GWxTD domain-containing protein.	0.732
SFB71898.1	SFB84923.1	SAMN05421780_10182	SAMN05421780_101749	Por secretion system C-terminal sorting domain-containing protein.	Por secretion system C-terminal sorting domain-containing protein.	0.499
SFB71898.1	SFC02672.1	SAMN05421780_10182	SAMN05421780_102317	Por secretion system C-terminal sorting domain-containing protein.	Por secretion system C-terminal sorting domain-containing protein.	0.710
SFB71898.1	SFC17565.1	SAMN05421780_10182	SAMN05421780_103165	Por secretion system C-terminal sorting domain-containing protein.	Por secretion system C-terminal sorting domain-containing protein.	0.586
SFB71898.1	SFC26541.1	SAMN05421780_10182	SAMN05421780_10465	Por secretion system C-terminal sorting domain-containing protein.	Hypothetical protein.	0.737
SFB71898.1	SFC26610.1	SAMN05421780_10182	SAMN05421780_10467	Por secretion system C-terminal sorting domain-containing protein.	TonB-dependent Receptor Plug Domain.	0.656
SFB71898.1	SFC37454.1	SAMN05421780_10182	SAMN05421780_10523	Por secretion system C-terminal sorting domain-containing protein.	Por secretion system C-terminal sorting domain-containing protein.	0.538
SFB71898.1	SFC42881.1	SAMN05421780_10182	SAMN05421780_105186	Por secretion system C-terminal sorting domain-containing protein.	Hypothetical protein.	0.681
SFB71898.1	SFC49257.1	SAMN05421780_10182	SAMN05421780_10641	Por secretion system C-terminal sorting domain-containing protein.	TonB-dependent Receptor Plug Domain.	0.675
SFB83787.1	SFB71898.1	SAMN05421780_101702	SAMN05421780_10182	GWxTD domain-containing protein.	Por secretion system C-terminal sorting domain-containing protein.	0.732
SFB83787.1	SFB84923.1	SAMN05421780_101702	SAMN05421780_101749	GWxTD domain-containing protein.	Por secretion system C-terminal sorting domain-containing protein.	0.680
SFB83787.1	SFC02672.1	SAMN05421780_101702	SAMN05421780_102317	GWxTD domain-containing protein.	Por secretion system C-terminal sorting domain-containing protein.	0.761
SFB83787.1	SFC26541.1	SAMN05421780_101702	SAMN05421780_10465	GWxTD domain-containing protein.	Hypothetical protein.	0.775
SFB83787.1	SFC26610.1	SAMN05421780_101702	SAMN05421780_10467	GWxTD domain-containing protein.	TonB-dependent Receptor Plug Domain.	0.775
SFB83787.1	SFC37454.1	SAMN05421780_101702	SAMN05421780_10523	GWxTD domain-containing protein.	Por secretion system C-terminal sorting domain-containing protein.	0.723
SFB83787.1	SFC42881.1	SAMN05421780_101702	SAMN05421780_105186	GWxTD domain-containing protein.	Hypothetical protein.	0.745
SFB83787.1	SFC49257.1	SAMN05421780_101702	SAMN05421780_10641	GWxTD domain-containing protein.	TonB-dependent Receptor Plug Domain.	0.774
SFB84923.1	SFB71898.1	SAMN05421780_101749	SAMN05421780_10182	Por secretion system C-terminal sorting domain-containing protein.	Por secretion system C-terminal sorting domain-containing protein.	0.499
SFB84923.1	SFB83787.1	SAMN05421780_101749	SAMN05421780_101702	Por secretion system C-terminal sorting domain-containing protein.	GWxTD domain-containing protein.	0.680
SFB84923.1	SFC02672.1	SAMN05421780_101749	SAMN05421780_102317	Por secretion system C-terminal sorting domain-containing protein.	Por secretion system C-terminal sorting domain-containing protein.	0.687

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Network Stats

number of nodes:

11

number of edges:

43

average node degree:

7.82

avg. local clustering coefficient:

0.921

expected number of edges:

11

PPI enrichment p-value:

2.22e-13

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000105

Histidine biosynthetic process

9 of 10

2.54

8.31

4.76e-18

GO:1901576

Organic substance biosynthetic process

11 of 722

0.77

0.78

5.44e-07

GO:0044249

Cellular biosynthetic process

10 of 679

0.76

0.72

9.24e-06

GO:0006807

Nitrogen compound metabolic process

10 of 1167

0.52

0.42

0.0013

GO:0044238

Primary metabolic process

11 of 1510

0.45

0.37

0.00086

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016763

Pentosyltransferase activity

3 of 14

1.92

1.15

0.0056

GO:0004424

Imidazoleglycerol-phosphate dehydratase activity

2 of 2

2.59

1.06

0.0119

GO:0004401

Histidinol-phosphatase activity

2 of 2

2.59

1.06

0.0119

GO:0000107

Imidazoleglycerol-phosphate synthase activity

2 of 2

2.59

1.06

0.0119

GO:0016829

Lyase activity

4 of 127

1.09

0.6

0.0312

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 1192

0.55

0.48

0.00010

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:933

Histidine biosynthesis

8 of 8

2.59

7.48

7.58e-16

CL:889

Phenylalanine, tyrosine and tryptophan biosynthesis, and Histidine biosynthetic process

9 of 32

2.04

5.53

7.20e-15

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00340

Histidine metabolism

9 of 28

2.09

6.05

6.56e-16

map01230

Biosynthesis of amino acids

9 of 139

1.4

2.39

1.84e-10

map01110

Biosynthesis of secondary metabolites

9 of 507

0.84

0.83

9.44e-06

map01100

Metabolic pathways

10 of 1519

0.41

0.32

0.0079

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005622

Intracellular

10 of 1333

0.46

0.32

0.0218

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0368

Histidine biosynthesis

8 of 9

2.54

7.55

3.03e-16

KW-0963

Cytoplasm

8 of 218

1.15

1.43

5.40e-07

KW-0456

Lyase

3 of 65

1.25

0.66

0.0299

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