STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdeA_3Methionine gamma-lyase. (462 aa)    
Predicted Functional Partners:
metX
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
 
 
 0.983
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.959
xecA1
2-hydroxypropyl-CoM lyase.
  
 
 0.949
metB
Cystathionine gamma-synthase.
 
 
 
0.898
mdeA_2
Methionine gamma-lyase.
 
 
 
0.885
patB
Cystathionine beta-lyase PatB.
   
 0.884
hom
Homoserine dehydrogenase.
  
 
 0.880
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
    
  0.870
cbs
Putative cystathionine beta-synthase.
  
 
 0.821
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.806
Your Current Organism:
Microbacterium ketosireducens
NCBI taxonomy Id: 92835
Other names: Aureibacterium ketoreductum, Aureobacterium ketoreductum, CIP 105732, DSM 12510, IFO 14548, JCM 12078, M. ketosireducens, NBRC 14548, VKM Ac-2082
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.