STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdlB(S)-mandelate dehydrogenase. (430 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.890
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
    
 0.882
accA1_1
Acetyl-/propionyl-coenzyme A carboxylase alpha chain; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.874
aceE
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.873
ldh2
L-lactate dehydrogenase 2; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
   
 
 0.872
ilvH
Putative acetolactate synthase small subunit.
  
 
  0.872
xsc
Sulfoacetaldehyde acetyltransferase; Belongs to the TPP enzyme family.
  
 
 0.869
ilvB1
Acetolactate synthase large subunit IlvB1.
  
 
 0.869
KJL37526.1
Putative FAD-linked oxidoreductase.
  
 0.868
KJL40069.1
Lactate 2-monooxygenase.
  
  
 
0.808
Your Current Organism:
Microbacterium ketosireducens
NCBI taxonomy Id: 92835
Other names: Aureibacterium ketoreductum, Aureobacterium ketoreductum, CIP 105732, DSM 12510, IFO 14548, JCM 12078, M. ketosireducens, NBRC 14548, VKM Ac-2082
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