STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gppA_1Ppx/GppA phosphatase. (542 aa)    
Predicted Functional Partners:
rsh
Metal dependent phosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
 
 0.906
gppA_2
Ppx/GppA phosphatase.
  
  
 
0.890
hda
dnaA protein; Belongs to the DnaA family.
       0.718
SFC28286.1
Predicted PurR-regulated permease PerM.
       0.718
addA
DNA helicase/exodeoxyribonuclease V, subunit A; Belongs to the helicase family. UvrD subfamily.
  
     0.637
cph2_2
Diguanylate cyclase/phosphodiesterase.
     
 0.543
SFC11382.1
Protein of unknown function.
  
     0.519
SFD07086.1
Hypothetical protein.
  
     0.497
SFD26282.1
Hypothetical protein.
  
     0.494
cgtA
GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
     
 0.491
Your Current Organism:
Epibacterium multivorans
NCBI taxonomy Id: 928856
Other names: CECT 7557, DSM 26470, E. multivorans, KCTC 23350, Tropicibacter multivorans, Tropicibacter multivorans Lucena et al. 2012, Tropicibacter sp. CECT 7557, strain MD5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.