STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshAGlutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (445 aa)    
Predicted Functional Partners:
gshB
Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
    
 0.958
ggt
Gamma-glutamyltranspeptidase / glutathione hydrolase.
     
  0.900
pepA
Leucyl aminopeptidase; Belongs to the peptidase M17 family.
     
  0.900
pepA-2
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
  0.900
pepN
Aminopeptidase N.
     
  0.900
ggt-3
Gamma-glutamyltranspeptidase / glutathione hydrolase.
     
  0.900
ilvE
Branched-chain amino acid aminotransferase.
     
  0.900
ilvE-2
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
gltD
Glutamate synthase (NADPH/NADH) small chain.
  
  
  0.824
putA
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 
  0.806
Your Current Organism:
Ketogulonicigenium robustum
NCBI taxonomy Id: 92947
Other names: K. robustum, KCTC 0858BP, Ketogulonicigenium robustum Urbance et al. 2001, Ketogulonigenium robustum, NRRL B-21627, strain X6L
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