STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFK02011.1PFAM: MutS domain V; COGs: COG0249 Mismatch repair ATPase (MutS family); InterPro IPR000432; KEGG: phe:Phep_0656 DNA mismatch repair protein MutS domain-containing protein; PFAM: DNA mismatch repair protein MutS, C-terminal; SMART: DNA mismatch repair protein MutS, C-terminal; SPTR: DNA mismatch repair protein MutS domain protein. (602 aa)    
Predicted Functional Partners:
AFK03458.1
DNA mismatch repair protein mutL; PFAM: MutL C terminal dimerisation domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA mismatch repair protein, C-terminal domain; TIGRFAM: DNA mismatch repair protein MutL; COGs: COG0323 DNA mismatch repair enzyme (predicted ATPase); HAMAP: DNA mismatch repair protein mutL; InterPro IPR014763:IPR003594:IPR013507:IPR014790; KEGG: sli:Slin_5569 DNA mismatch repair protein MutL; PFAM: MutL, C-terminal, dimerisation; DNA mismatch repair protein, C-terminal; ATP-binding region, ATPase-like; SPTR: DNA mismatch repair protein MutL; TIGRFAM: [...]
 
 0.995
AFK05225.1
DNA polymerase I; PFAM: 5'-3' exonuclease, C-terminal SAM fold; 3'-5' exonuclease; 5'-3' exonuclease, N-terminal resolvase-like domain; DNA polymerase family A; TIGRFAM: DNA polymerase I; COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR002421:IPR008918:IPR002562:IPR001098:IPR 018320:IPR020046:IPR020047; KEGG: sli:Slin_0543 DNA polymerase I; PFAM: DNA-directed DNA polymerase, family A, palm domain; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; SMART: 5'-3' exonuclease, N-terminal; Helix-h [...]
   
 0.963
AFK02656.1
PFAM: DNA polymerase III beta subunit, C-terminal domain; DNA polymerase III beta subunit, N-terminal domain; DNA polymerase III beta subunit, central domain; TIGRFAM: DNA polymerase III, beta subunit; COGs: COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); InterPro IPR001001; KEGG: dfe:Dfer_3720 DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain; SMART: DNA polymerase III, beta chain; SPTR: DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta chain.
   
 0.953
AFK02903.1
3'-5' exonuclease, PolB-like protein; PFAM: Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; InterPro IPR019288; KEGG: dfe:Dfer_3714 hypothetical protein; PFAM: 3'-5' exonuclease, PolB-like; SPTR: Putative uncharacterized protein.
   
 0.803
AFK05014.1
PFAM: Histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase; COGs: COG0141 Histidinol dehydrogenase; HAMAP: Histidinol dehydrogenase, prokaryotic-type; InterPro IPR012131; KEGG: sli:Slin_1784 histidinol dehydrogenase; PFAM: Histidinol dehydrogenase, prokaryotic-type; SPTR: Histidinol dehydrogenase; TIGRFAM: Histidinol dehydrogenase, prokaryotic-type.
   
 0.765
AFK02491.1
PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: asparaginyl-tRNA synthetase; COGs: COG0017 Aspartyl/asparaginyl-tRNA synthetase; HAMAP: Asparaginyl-tRNA synthetase; InterPro IPR004522:IPR004365:IPR004364; KEGG: lby:Lbys_3177 asparaginyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; SPTR: Asparaginyl-tRNA synthetase; TIGRFAM: Asparaginyl-tRNA synthetase, class IIb.
   
 0.762
AFK04131.1
PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit; TIGRFAM: DNA phosphorothioation system restriction enzyme; COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR014001:IPR001650:IPR006935; KEGG: pru:PRU_1053 type III restriction-modification system subunit Res; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: DNA repair helicase.
   
 0.751
AFK02040.1
UvrABC system protein C; PFAM: UvrC Helix-hairpin-helix N-terminal; GIY-YIG catalytic domain; TIGRFAM: excinuclease ABC, C subunit; COGs: COG0322 Nuclease subunit of the excinuclease complex; HAMAP: UvrABC system protein C; InterPro IPR000305:IPR001162:IPR004791; KEGG: lby:Lbys_0072 excinuclease ABC, C subunit; PFAM: Excinuclease ABC, C subunit, C-terminal; Excinuclease ABC, C subunit, N-terminal; SMART: Excinuclease ABC, C subunit, N-terminal; SPTR: UvrABC system protein C; TIGRFAM: Excinuclease ABC, C subunit.
    
 0.728
AFK02927.1
PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; Beta-Casp domain; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; InterPro IPR011108; KEGG: sli:Slin_5075 beta-lactamase; PFAM: RNA-metabolising metallo-beta-lactamase; SPTR: Beta-lactamase domain protein.
   
 0.728
AFK04987.1
PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; Beta-Casp domain; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; InterPro IPR011108; KEGG: lby:Lbys_0310 RNA-metabolising metallo-beta-lactamase; PFAM: RNA-metabolising metallo-beta-lactamase; SPTR: RNA-metabolising metallo-beta-lactamase.
   
 0.728
Your Current Organism:
Emticicia oligotrophica
NCBI taxonomy Id: 929562
Other names: E. oligotrophica DSM 17448, Emticicia oligotrophica DSM 17448, Emticicia oligotrophica GPTSA100-15, Emticicia oligotrophica str. DSM 17448, Emticicia oligotrophica strain DSM 17448
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