STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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[Homology]
Score
AFK02247.1AAA ATPase central domain protein; PFAM: MgsA AAA+ ATPase C terminal; ATPase family associated with various cellular activities (AAA); COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003593:IPR008824:IPR003959; KEGG: dfe:Dfer_5733 AAA ATPase central domain protein; PFAM: ATPase, AAA-type, core; DNA helicase, Holliday junction RuvB type, N-terminal; SMART: ATPase, AAA+ type, core; SPTR: AAA ATPase central domain protein. (420 aa)    
Predicted Functional Partners:
AFK03450.1
ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterPro IPR018329:IPR011545:IPR001650:IPR014001; KEGG: sli:Slin_5465 ATP-dependent DNA helicase, RecQ family; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: ATP-dependent DNA helicase, RecQ family; TIGRFAM: DNA helicase, ATP-dependent, RecQ type, N-terminal.
  
 0.798
AFK03782.1
ATP-dependent DNA helicase RecQ; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterProIPR014001:IPR001650:IPR002121:IPR011545:IPR 018982:IPR006293:IPR018329; KEGG: lby:Lbys_0471 ATP-dependent DNA helicase RecQ; PFAM: DNA/RNA helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; RQC domain; Helicase/RNase D C-terminal, HRDC domain; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal [...]
  
 0.796
AFK04729.1
ATP-dependent DNA helicase RecQ; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterProIPR011545:IPR001650:IPR018982:IPR002121:IPR 014001:IPR006293:IPR018329; KEGG: dfe:Dfer_3877 ATP-dependent DNA helicase RecQ; PFAM: RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; SMART: DNA/RNA helicase, C-terminal; DEAD-like helicase, N-terminal [...]
  
 0.796
AFK05296.1
PFAM: DnaB-like helicase N terminal domain; DnaB-like helicase C terminal domain; TIGRFAM: replicative DNA helicase; COGs: COG0305 Replicative DNA helicase; InterPro IPR007692:IPR007693:IPR007694; KEGG: dfe:Dfer_1073 replicative DNA helicase; PFAM: DNA helicase, DnaB-like, C-terminal; DNA helicase, DnaB-like, N-terminal; SPTR: Replicative DNA helicase; TIGRFAM: DNA helicase, DnaB type.
    
 0.749
AFK02644.1
Primosomal protein N; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: primosomal protein N'; COGs: COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; InterPro IPR005259:IPR014001:IPR001650:IPR011545; KEGG: dfe:Dfer_3377 primosomal protein N'; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: Primosomal protein N'; TIGRFAM: Primosomal protein n.
  
 
  0.715
AFK02479.1
PFAM: Exonuclease; COGs: COG0847 DNA polymerase III epsilon subunit and related 3'-5' exonuclease; InterPro IPR006055:IPR013520; KEGG: ppn:Palpr_3000 exonuclease RNAse t and DNA polymerase III; PFAM: Exonuclease, RNase T/DNA polymerase III; SMART: Exonuclease; SPTR: Exonuclease RNase T and DNA polymerase III.
  
 
  0.669
AFK02625.1
PFAM: Exonuclease; COGs: COG0847 DNA polymerase III epsilon subunit and related 3'-5' exonuclease; InterPro IPR006055:IPR013520; KEGG: lby:Lbys_2788 exonuclease RNase T and DNA polymerase III; PFAM: Exonuclease, RNase T/DNA polymerase III; SMART: Exonuclease; SPTR: Exonuclease RNase T and DNA polymerase III.
  
 
  0.669
AFK05225.1
DNA polymerase I; PFAM: 5'-3' exonuclease, C-terminal SAM fold; 3'-5' exonuclease; 5'-3' exonuclease, N-terminal resolvase-like domain; DNA polymerase family A; TIGRFAM: DNA polymerase I; COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR002421:IPR008918:IPR002562:IPR001098:IPR 018320:IPR020046:IPR020047; KEGG: sli:Slin_0543 DNA polymerase I; PFAM: DNA-directed DNA polymerase, family A, palm domain; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; SMART: 5'-3' exonuclease, N-terminal; Helix-h [...]
 
  
 0.563
AFK04428.1
NAD+ synthetase; PFAM: NAD synthase; Carbon-nitrogen hydrolase; TIGRFAM: NAD+ synthetase; COGs: COG0171 NAD synthase; InterPro IPR003010:IPR003694; KEGG: dfe:Dfer_2832 NAD+ synthetase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; NAD+ synthase; SPTR: NAD+ synthetase; TIGRFAM: NAD+ synthase.
  
    0.538
AFK02246.1
1,4-alpha-glucan-branching enzyme; PFAM: Alpha amylase, C-terminal all-beta domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain; TIGRFAM: alpha-1,4-glucan:alpha-1,4-glucan 6-glycosyltransferase; COGs: COG0296 1 4-alpha-glucan branching enzyme; HAMAP: 1,4-alpha-glucan branching enzyme, core region; InterProIPR006589:IPR006407:IPR004193:IPR006047:IPR 006048; KEGG: lby:Lbys_3517 1,4-alpha-glucan branching enzyme; PFAM: Alpha-amylase, C-terminal all beta; Glycoside hydrolase, family 13, N-terminal; Glycosyl hydrolase, family 13, catalytic [...]
       0.507
Your Current Organism:
Emticicia oligotrophica
NCBI taxonomy Id: 929562
Other names: E. oligotrophica DSM 17448, Emticicia oligotrophica DSM 17448, Emticicia oligotrophica GPTSA100-15, Emticicia oligotrophica str. DSM 17448, Emticicia oligotrophica strain DSM 17448
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