STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFK02312.1PFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase; TIGRFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase; COGs: COG0108 3 4-dihydroxy-2-butanone 4-phosphate synthase; HAMAP: GTP cyclohydrolase-2; InterPro IPR000422:IPR000926; KEGG: lby:Lbys_1704 gtp cyclohydrolase II; PFAM: DHBP synthase RibB; GTP cyclohydrolase II; SPTR: Riboflavin biosynthesis protein ribBA; TIGRFAM: DHBP synthase RibB; GTP cyclohydrolase II. (401 aa)    
Predicted Functional Partners:
AFK02971.1
PFAM: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase; COGs: COG0054 Riboflavin synthase beta-chain; HAMAP: 6,7-dimethyl-8-ribityllumazine synthase; InterPro IPR002180; KEGG: lby:Lbys_2057 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase; SPTR: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase.
 
 0.999
AFK03619.1
Riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin biosynthesis protein RibD; COGs: COG0117 Pyrimidine deaminase; InterPro IPR002125:IPR002734:IPR004794; KEGG: sli:Slin_2937 riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase, zinc-binding; Bacterial bifunctional deaminase-reductase, C-terminal; SPTR: Riboflavin biosynthesis protein RibD; TIGRFAM: Riboflavin biosynthesis protein RibD.
 0.999
AFK04458.1
PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit; COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: dfe:Dfer_2926 riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein.
 
 0.999
AFK05250.1
PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; COGs: COG0302 GTP cyclohydrolase I; HAMAP: GTP cyclohydrolase I; InterPro IPR001474:IPR020602; KEGG: lby:Lbys_0690 gtp cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I.
 
 
 0.950
AFK03109.1
PFAM: Nucleoside diphosphate kinase; COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: lby:Lbys_2896 nucleoside-diphosphate kinase; PFAM: Nucleoside diphosphate kinase, core; SMART: Nucleoside diphosphate kinase, core; SPTR: Nucleoside-diphosphate kinase.
  
 0.884
AFK02531.1
PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; COGs: COG0052 Ribosomal protein S2; InterPro IPR005706:IPR001865; KEGG: lby:Lbys_2854 ssu ribosomal protein s2p; PFAM: Ribosomal protein S2; SPTR: 30S ribosomal protein S2; TIGRFAM: Ribosomal protein S2, bacteria/mitochondria/plastid.
   
 
 0.880
AFK04070.1
(p)ppGpp synthetase I, SpoT/RelA; PFAM: HD domain; TGS domain; Region found in RelA / SpoT proteins; TIGRFAM: (p)ppGpp synthetase, RelA/SpoT family; COGs: COG0317 Guanosine polyphosphate pyrophosphohydrolase/synthetase; InterProIPR003607:IPR004811:IPR006674:IPR007685:IPR 004095; KEGG: lby:Lbys_2933 (p)ppGpp synthetase I, spot/RelA; PFAM: RelA/SpoT; Metal-dependent phosphohydrolase, HD region, subdomain; TGS; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: (P)ppGpp synthetase I, SpoT/RelA; TIGRFAM: RelA/SpoT protein.
  
 
 0.836
AFK04397.1
PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001789:IPR001054; KEGG: sli:Slin_5021 adenylate/guanylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase.
    
 0.822
AFK02843.1
PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase; COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR001093:IPR000644:IPR005990; KEGG: lby:Lbys_2873 inosine-5'-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core; SPTR: Inosine-5'-monophosphate dehydrogenase; TIGRFAM: IMP dehydrogenase.
  
  
 0.814
AFK02291.1
Adenylate cyclase; PFAM: CYTH domain; COGs: COG2954 conserved hypothetical protein; InterPro IPR008172; KEGG: chu:CHU_0188 adenylate cyclase; PFAM: Adenylate cyclase; SPTR: Adenylate cyclase.
    
  0.800
Your Current Organism:
Emticicia oligotrophica
NCBI taxonomy Id: 929562
Other names: E. oligotrophica DSM 17448, Emticicia oligotrophica DSM 17448, Emticicia oligotrophica GPTSA100-15, Emticicia oligotrophica str. DSM 17448, Emticicia oligotrophica strain DSM 17448
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