STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
AFK02318.1Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; CHASE3 domain; COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterPro IPR003661:IPR003594:IPR007891; KEGG: hch:HCH_04931 signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; CHASE3; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, [...] (485 aa)    
Predicted Functional Partners:
AFK02058.1
PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003018:IPR013656:IPR003661:IPR003594:IPR 001789:IPR008207:IPR000014:IPR001610; KEGG: fjo:Fjoh_3925 GAF sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; GAF; Signal transduction response regulator, receiver reg [...]
 
 0.967
AFK04965.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR013767:IPR003661:IPR003594:IPR 001789:IPR001610; KEGG: cts:Ctha_0019 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; Sign [...]
 
 0.967
AFK02319.1
PFAM: Response regulator receiver domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: psm:PSM_A0656 two-component response regulator; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Two-component response regulator.
 
 
 0.961
AFK04976.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR013655:IPR003661:IPR003594:IPR 001789:IPR008207:IPR001610; KEGG: sli:Slin_6270 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-3; Signal transduction response regulator, receiver region; Signal transduction [...]
 
0.950
AFK02027.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold; Hpt domain; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR013656:IPR003018:IPR013767:IPR003661:IPR 003594:IPR001789:IPR008207:IPR000014:IPR001610; KEGG: lby:Lbys_1292 multi-sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; [...]
 
0.947
AFK02558.1
PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR013767; KEGG: sli:Slin_6270 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; Signal transduction response regulator, receiver [...]
 
0.936
AFK02313.1
Signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR001789:IPR000014:IPR003661:IPR003594:IPR 013767; KEGG: dfe:Dfer_2748 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; Signa [...]
 
  
 0.889
AFK02314.1
PFAM: Response regulator receiver domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: ttu:TERTU_3627 response regulator receiver domain-containing protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator Rcp1.
 
  
 0.880
AFK05402.1
Putative PAS/PAC sensor protein; PFAM: Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR000014:IPR013767; KEGG: mtt:Ftrac_2272 pas/pac sensor protein; PFAM: Signal transduction response regulator, receiver region; PAS fold; SMART: Signal transduction response regulator, receiver region; PAS; SPTR: Putative PAS/PAC sensor protein; TIGRFAM: PAS.
 
 0.880
AFK05403.1
PFAM: Response regulator receiver domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: mtt:Ftrac_2273 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein.
 
 
 0.865
Your Current Organism:
Emticicia oligotrophica
NCBI taxonomy Id: 929562
Other names: E. oligotrophica DSM 17448, Emticicia oligotrophica DSM 17448, Emticicia oligotrophica GPTSA100-15, Emticicia oligotrophica str. DSM 17448, Emticicia oligotrophica strain DSM 17448
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