STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
AFK03036.1Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR006258:IPR013027:IPR004099; KEGG: lby:Lbys_2718 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: Dihydrolipoamide dehydrogenase. (463 aa)    
Predicted Functional Partners:
AFK02559.1
Transketolase central region; PFAM: Dehydrogenase E1 component; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR001017:IPR005475:IPR005476; KEGG: sli:Slin_4914 transketolase; PFAM: Transketolase-like, pyrimidine-binding domain; Dehydrogenase, E1 component; Transketolase, C-terminal; SPTR: Transketolase domain protein.
 
 0.999
AFK05289.1
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR006257:IPR000089:IPR004167:IPR001078; KEGG: lby:Lbys_1333 catalytic domaiN-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; [...]
 0.999
AFK02161.1
2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: 2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component); COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR004167:IPR001078:IPR006255; KEGG: lby:Lbys_3489 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: 2-oxoacid dehydrogenase acyltransferase [...]
 0.998
AFK03577.1
Transketolase central region; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475:IPR005476; KEGG: lby:Lbys_1402 transketolase central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; SPTR: Transketolase central region.
 0.998
AFK05209.1
Catalytic domain-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR004167:IPR001078; KEGG: lby:Lbys_3580 catalytic domaiN-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding; SPTR: Catalytic domain-containing prote [...]
 0.998
AFK03037.1
PFAM: Dehydrogenase E1 component; TIGRFAM: pyruvate dehydrogenase E1 component, alpha subunit; COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR017597:IPR001017; KEGG: lby:Lbys_2059 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; PFAM: Dehydrogenase, E1 component; SPTR: Pyruvate dehydrogenase (Acetyl-transferring) E1 component, alpha subunit; TIGRFAM: Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y.
 
 0.997
AFK02442.1
Catalytic domain-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR001078; KEGG: lby:Lbys_3077 catalytic domaiN-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; SPTR: Catalytic domain-containing protein of components of various dehydrogenase complexes.
 
 0.995
AFK02160.1
2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component; COGs: COG0567 2-oxoglutarate dehydrogenase complex dehydrogenase (E1); InterPro IPR001017:IPR005475:IPR011603; KEGG: lby:Lbys_3488 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase-like, pyrimidine-binding domain; Dehydrogenase, E1 component; SPTR: 2-oxoglutarate dehydrogenase, E1 subunit; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component.
 
 0.994
AFK05039.1
PFAM: Glycine cleavage H-protein; TIGRFAM: glycine cleavage system H protein; COGs: COG0509 Glycine cleavage system H protein (lipoate-binding); HAMAP: Glycine cleavage H-protein; InterPro IPR017453:IPR002930; KEGG: lby:Lbys_0445 glycine cleavage system H protein; PFAM: Glycine cleavage H-protein; SPTR: Glycine cleavage system H protein; TIGRFAM: Glycine cleavage H-protein, subgroup.
 
  
 0.990
AFK01701.1
PFAM: Glycine cleavage system P-protein; TIGRFAM: glycine dehydrogenase (decarboxylating); COGs: COG1003 Glycine cleavage system protein P (pyridoxal-binding) C-terminal domain; HAMAP: Glycine cleavage system P-protein; InterPro IPR003437:IPR020580; KEGG: dfe:Dfer_4078 glycine dehydrogenase; PFAM: Glycine cleavage system P-protein, N-terminal; SPTR: Glycine dehydrogenase [decarboxylating]; TIGRFAM: Glycine cleavage system P-protein.
 
 
 0.988
Your Current Organism:
Emticicia oligotrophica
NCBI taxonomy Id: 929562
Other names: E. oligotrophica DSM 17448, Emticicia oligotrophica DSM 17448, Emticicia oligotrophica GPTSA100-15, Emticicia oligotrophica str. DSM 17448, Emticicia oligotrophica strain DSM 17448
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