STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFK04258.1Threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase; COGs: COG0498 Threonine synthase; InterPro IPR001926:IPR004450; KEGG: dfe:Dfer_3806 threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Threonine synthase; TIGRFAM: Threonine synthase. (436 aa)    
Predicted Functional Partners:
AFK04790.1
PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: homoserine kinase; COGs: COG0083 Homoserine kinase; HAMAP: Homoserine kinase; InterPro IPR000870:IPR006204:IPR013750; KEGG: lby:Lbys_0630 homoserine kinase; PFAM: GHMP kinase; GHMP kinase, C-terminal; SPTR: Homoserine kinase; TIGRFAM: Homoserine kinase.
 
 0.999
AFK04814.1
Aspartate kinase; PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase; ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; COGs: COG0527 Aspartokinase; InterProIPR001341:IPR001048:IPR002912:IPR005106:IPR 001342; KEGG: dfe:Dfer_3152 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region.
 
 
 0.989
AFK02942.1
Threonine dehydratase; PFAM: C-terminal regulatory domain of Threonine dehydratase; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine ammonia-lyase, biosynthetic, long form; threonine dehydratase; COGs: COG1171 Threonine dehydratase; InterPro IPR001926:IPR001721:IPR011820; KEGG: sli:Slin_5911 threonine dehydratase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Threonine dehydratase, C-terminal; SPTR: Threonine dehydratase; TIGRFAM: Threonine dehydratase.
  
 
 0.951
AFK04487.1
Aromatic amino acid beta-eliminating lyase/threonine aldolase; PFAM: Beta-eliminating lyase; COGs: COG2008 Threonine aldolase; InterPro IPR001597; KEGG: dfe:Dfer_4745 threonine aldolase; PFAM: Aromatic amino acid beta-eliminating lyase/threonine aldolase; SPTR: Threonine aldolase.
  
 0.925
AFK03565.1
PFAM: Aminotransferase class-V; TIGRFAM: phosphoserine aminotransferase, putative; phosphoserine aminotransferase; COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: lby:Lbys_1176 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; SPTR: Aminotransferase class V.
   
 0.916
AFK04831.1
PFAM: Aminotransferase class-V; TIGRFAM: phosphoserine aminotransferase, putative; COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: dfe:Dfer_5113 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; SPTR: Phosphoserine aminotransferase, Mycobacterial type, putative.
   
 0.916
AFK04477.1
PFAM: NAD dependent epimerase/dehydratase family; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: dfe:Dfer_4406 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase.
   
 
  0.900
AFK02849.1
PFAM: Aconitase C-terminal domain; TIGRFAM: 3-isopropylmalate dehydratase, small subunit; COGs: COG0066 3-isopropylmalate dehydratase small subunit; InterPro IPR000573:IPR004431; KEGG: dfe:Dfer_3673 3-isopropylmalate dehydratase, small subunit; PFAM: Aconitase A/isopropylmalate dehydratase small subunit, swivel; SPTR: 3-isopropylmalate dehydratase, small subunit; TIGRFAM: 3-isopropylmalate dehydratase, small subunit region.
 
  
 0.851
AFK02972.1
PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR001341; KEGG: dfe:Dfer_3817 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; SPTR: Aspartokinase; TIGRFAM: Aspartate kinase region.
 
 
 0.802
AFK04257.1
PilT protein domain protein; PFAM: PIN domain; InterPro IPR002716; KEGG: shg:Sph21_0441 PilT protein domain protein; PFAM: PilT protein, N-terminal; SPTR: Glr2432 protein.
       0.760
Your Current Organism:
Emticicia oligotrophica
NCBI taxonomy Id: 929562
Other names: E. oligotrophica DSM 17448, Emticicia oligotrophica DSM 17448, Emticicia oligotrophica GPTSA100-15, Emticicia oligotrophica str. DSM 17448, Emticicia oligotrophica strain DSM 17448
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.