STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFK05322.1FolC bifunctional protein; PFAM: Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR001645:IPR013221:IPR004101; KEGG: psn:Pedsa_1924 FolC bifunctional protein; PFAM: Mur ligase, central; Mur ligase, C-terminal; SPTR: Tetrahydrofolate synthase; TIGRFAM: Folylpolyglutamate synthetase. (430 aa)    
Predicted Functional Partners:
AFK04998.1
Dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase; COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: mtt:Ftrac_3719 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase.
 
 0.997
AFK03160.1
PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: sli:Slin_4404 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
  
 0.953
AFK02580.1
PFAM: Dihydrofolate reductase; COGs: COG0262 Dihydrofolate reductase; InterPro IPR001796; KEGG: hch:HCH_05856 dihydrofolate reductase; PFAM: Dihydrofolate reductase region; SPTR: Dihydrofolate reductase type I; trimethoprim resistance.
     
 0.911
AFK04557.1
PFAM: Thymidylate synthase; TIGRFAM: thymidylate synthase; COGs: COG0207 Thymidylate synthase; HAMAP: Thymidylate synthase; InterPro IPR000398; KEGG: sli:Slin_2832 thymidylate synthase; PFAM: Thymidylate synthase, C-terminal; SPTR: Thymidylate synthase; TIGRFAM: Thymidylate synthase, C-terminal.
     
 0.842
AFK05323.1
PFAM: Putative methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase; COGs: COG0220 S-adenosylmethionine-dependent methyltransferase; HAMAP: tRNA (guanine-N(7)-)-methyltransferase; InterPro IPR003358; KEGG: lby:Lbys_0927 tRNA (guanine-n(7)-)-methyltransferase; PFAM: tRNA (guanine-N-7) methyltransferase; SPTR: tRNA (guanine-N(7)-)-methyltransferase; TIGRFAM: tRNA (guanine-N-7) methyltransferase.
       0.686
AFK03842.1
PFAM: Serine hydroxymethyltransferase; COGs: COG0112 Glycine/serine hydroxymethyltransferase; InterPro IPR001085; KEGG: dfe:Dfer_3814 serine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase; SPTR: Serine hydroxymethyltransferase.
  
 0.675
AFK05250.1
PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; COGs: COG0302 GTP cyclohydrolase I; HAMAP: GTP cyclohydrolase I; InterPro IPR001474:IPR020602; KEGG: lby:Lbys_0690 gtp cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I.
 
  
 0.674
AFK04903.1
PFAM: GMP synthase C terminal domain; Glutamine amidotransferase class-I; NAD synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit; COGs: COG0519 GMP synthase PP-ATPase domain/subunit; HAMAP: GMP synthase [glutamine-hydrolyzing]; InterPro IPR004739:IPR001674:IPR000991:IPR018318; KEGG: sli:Slin_2862 GMP synthase, large subunit; PFAM: GMP synthase, C-terminal; Glutamine amidotransferase class-I, C-terminal; tRNA methyl transferase-like; SPTR: GMP synthase [glutamine-hydrolyzing]; TIGR [...]
 
  
 0.662
AFK05321.1
KEGG: lby:Lbys_0929 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.607
AFK03254.1
Nucleoside-triphosphatase rdgB; PFAM: Ham1 family; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; COGs: COG0127 Xanthosine triphosphate pyrophosphatase; HAMAP: Nucleoside-triphosphatase rdgB; InterPro IPR002637; KEGG: bvu:BVU_1146 putative deoxyribonucleoside-triphosphatase; PFAM: Ham1-like protein; SPTR: Nucleoside-triphosphatase; TIGRFAM: Ham1-like protein.
 
  
 0.599
Your Current Organism:
Emticicia oligotrophica
NCBI taxonomy Id: 929562
Other names: E. oligotrophica DSM 17448, Emticicia oligotrophica DSM 17448, Emticicia oligotrophica GPTSA100-15, Emticicia oligotrophica str. DSM 17448, Emticicia oligotrophica strain DSM 17448
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