node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
folB | folC | GCA_002079865_00211 | GCA_002079865_01704 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydrofolate synthase/folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 0.721 |
folB | folP | GCA_002079865_00211 | GCA_002079865_00616 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase. | 0.997 |
folB | ftsH_2 | GCA_002079865_00211 | GCA_002079865_00615 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.434 |
folC | folB | GCA_002079865_01704 | GCA_002079865_00211 | Dihydrofolate synthase/folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.721 |
folC | folP | GCA_002079865_01704 | GCA_002079865_00616 | Dihydrofolate synthase/folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase. | 0.998 |
folP | folB | GCA_002079865_00616 | GCA_002079865_00211 | Dihydropteroate synthase. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.997 |
folP | folC | GCA_002079865_00616 | GCA_002079865_01704 | Dihydropteroate synthase. | Dihydrofolate synthase/folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 0.998 |
folP | ftsH_2 | GCA_002079865_00616 | GCA_002079865_00615 | Dihydropteroate synthase. | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.863 |
folP | glmM_1 | GCA_002079865_00616 | GCA_002079865_00617 | Dihydropteroate synthase. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.944 |
folP | guaB_2 | GCA_002079865_00616 | GCA_002079865_03242 | Dihydropteroate synthase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.616 |
folP | pabB | GCA_002079865_00616 | GCA_002079865_01806 | Dihydropteroate synthase. | Aminodeoxychorismate synthase component 1. | 0.599 |
folP | pabC | GCA_002079865_00616 | GCA_002079865_03056 | Dihydropteroate synthase. | Aminodeoxychorismate lyase. | 0.927 |
folP | ribH | GCA_002079865_00616 | GCA_002079865_02398 | Dihydropteroate synthase. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.674 |
folP | tpiA | GCA_002079865_00616 | GCA_002079865_00618 | Dihydropteroate synthase. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.646 |
folP | trpG | GCA_002079865_00616 | GCA_002079865_02845 | Dihydropteroate synthase. | Anthranilate synthase component 2. | 0.744 |
ftsH_2 | folB | GCA_002079865_00615 | GCA_002079865_00211 | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.434 |
ftsH_2 | folP | GCA_002079865_00615 | GCA_002079865_00616 | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Dihydropteroate synthase. | 0.863 |
ftsH_2 | glmM_1 | GCA_002079865_00615 | GCA_002079865_00617 | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.855 |
ftsH_2 | guaB_2 | GCA_002079865_00615 | GCA_002079865_03242 | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.478 |
ftsH_2 | tpiA | GCA_002079865_00615 | GCA_002079865_00618 | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.788 |