STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
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[Homology]
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ilvAL-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (415 aa)    
Predicted Functional Partners:
SFE94760.1
Homoserine dehydrogenase.
  
 
 0.960
SFE69538.1
Acetolactate synthase, small subunit.
  
 
 0.901
SFE33195.1
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.867
SFE94775.1
L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
 
0.835
SFE98641.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.834
SFE33501.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 0.829
SFE33476.1
Homocysteine S-methyltransferase.
  
 0.787
ilvD-2
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.773
SFE69519.1
Acetolactate synthase, large subunit.
 
 0.756
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.751
Your Current Organism:
Alteribacillus iranensis
NCBI taxonomy Id: 930128
Other names: A. iranensis, Alteribacillus iranensis (Bagheri et al. 2012) Azmatunnisa Begum et al. 2016, Bacillus iranensis, Bacillus iranensis Bagheri et al. 2012, Bacillus sp. X5B(2010), DSM 23995, IBRC 10446, strain X5B
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