Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (376 aa)    
Predicted Functional Partners:
DRD2
Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.
   
0.907
CRH
Corticotropin releasing hormone.
     
 0.880
DRD3
Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.
   
 0.852
GNG12
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 0.846
GNB5
G protein subunit beta 5.
    
 0.844
G3VSZ6_SARHA
Uncharacterized protein.
    
 0.830
GNA15
G protein subunit alpha 15.
    
 0.830
TSHB
Thyroid stimulating hormone subunit beta.
   
 
 0.828
GNG8
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.825
GNG13
G protein subunit gamma 13.
    
  0.825
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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