BCR protein (Sarcophilus harrisii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

BCR

Uncharacterized protein. (623 aa)

Predicted Functional Partners:

GRB2

0.954

ABL1

0.930

CRKL

0.915

CBL

0.912

LOC111720510

0.903

STAT5B

0.903

SHC3

0.900

SHC1

0.900

SHC2

0.900

SHC4

0.900

Your Current Organism:

Sarcophilus harrisii

NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	BCR	ENSSHAP00000019280	ENSSHAP00000001366	Tyrosine-protein kinase.	Uncharacterized protein.	0.930
ABL1	CBL	ENSSHAP00000019280	ENSSHAP00000009276	Tyrosine-protein kinase.	Cbl proto-oncogene.	0.951
ABL1	CRKL	ENSSHAP00000019280	ENSSHAP00000001508	Tyrosine-protein kinase.	CRK like proto-oncogene, adaptor protein.	0.972
ABL1	GRB2	ENSSHAP00000019280	ENSSHAP00000021710	Tyrosine-protein kinase.	Growth factor receptor bound protein 2.	0.963
ABL1	LOC111720510	ENSSHAP00000019280	ENSSHAP00000000119	Tyrosine-protein kinase.	STAT_bind domain-containing protein.	0.921
ABL1	SHC1	ENSSHAP00000019280	ENSSHAP00000005170	Tyrosine-protein kinase.	SHC adaptor protein 1.	0.927
ABL1	SHC2	ENSSHAP00000019280	ENSSHAP00000013356	Tyrosine-protein kinase.	Uncharacterized protein.	0.920
ABL1	SHC3	ENSSHAP00000019280	ENSSHAP00000002029	Tyrosine-protein kinase.	SHC adaptor protein 3.	0.927
ABL1	SHC4	ENSSHAP00000019280	ENSSHAP00000018142	Tyrosine-protein kinase.	SHC adaptor protein 4.	0.920
ABL1	STAT5B	ENSSHAP00000019280	ENSSHAP00000004406	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.921
BCR	ABL1	ENSSHAP00000001366	ENSSHAP00000019280	Uncharacterized protein.	Tyrosine-protein kinase.	0.930
BCR	CBL	ENSSHAP00000001366	ENSSHAP00000009276	Uncharacterized protein.	Cbl proto-oncogene.	0.912
BCR	CRKL	ENSSHAP00000001366	ENSSHAP00000001508	Uncharacterized protein.	CRK like proto-oncogene, adaptor protein.	0.915
BCR	GRB2	ENSSHAP00000001366	ENSSHAP00000021710	Uncharacterized protein.	Growth factor receptor bound protein 2.	0.954
BCR	LOC111720510	ENSSHAP00000001366	ENSSHAP00000000119	Uncharacterized protein.	STAT_bind domain-containing protein.	0.903
BCR	SHC1	ENSSHAP00000001366	ENSSHAP00000005170	Uncharacterized protein.	SHC adaptor protein 1.	0.900
BCR	SHC2	ENSSHAP00000001366	ENSSHAP00000013356	Uncharacterized protein.	Uncharacterized protein.	0.900
BCR	SHC3	ENSSHAP00000001366	ENSSHAP00000002029	Uncharacterized protein.	SHC adaptor protein 3.	0.900
BCR	SHC4	ENSSHAP00000001366	ENSSHAP00000018142	Uncharacterized protein.	SHC adaptor protein 4.	0.900
BCR	STAT5B	ENSSHAP00000001366	ENSSHAP00000004406	Uncharacterized protein.	Signal transducer and activator of transcription.	0.903