Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ULK4Protein kinase domain-containing protein. (533 aa)    
Predicted Functional Partners:
SUFU
SUFU negative regulator of hedgehog signaling.
    
 0.824
CHRNA2
Cholinergic receptor nicotinic alpha 2 subunit.
      
 0.761
CHRNA5
Cholinergic receptor nicotinic alpha 5 subunit.
      
 0.761
CHRNA9
Cholinergic receptor nicotinic alpha 9 subunit.
      
 0.753
CHRNA4
Cholinergic receptor nicotinic alpha 4 subunit.
      
 0.652
ATG9B
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
      
 0.592
STK36
Serine/threonine kinase 36.
    
 
 0.579
CHRNB3
Cholinergic receptor nicotinic beta 3 subunit.
      
 0.564
LOC100921384
Aa_trans domain-containing protein.
      
 0.563
CCDC149
Coiled-coil domain containing 149.
      
 0.563
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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