STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APOEUncharacterized protein. (256 aa)    
Predicted Functional Partners:
LRP2
Uncharacterized protein.
    
 0.957
LRP1
LDL receptor related protein 1.
    
 0.955
LPL
Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
     
 0.919
APOA4
Uncharacterized protein.
     
 0.907
G3VJ24_SARHA
Vitellogenin domain-containing protein.
   
 0.899
VLDLR
Very low density lipoprotein receptor.
    
 0.893
APOC2
Uncharacterized protein.
    
 0.893
APOA2
Apolipoprotein A2.
    
 0.880
APP
Amyloid beta precursor protein.
    
 0.877
APOA1
Uncharacterized protein.
   
 
 0.876
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.