FGD4 protein (Sarcophilus harrisii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

FGD4

Uncharacterized protein. (424 aa)

Predicted Functional Partners:

CDC42

0.875

SH3TC2

0.759

FGD3

0.733

GNG12

0.596

PIGN

0.577

ESAM

0.558

FGD1

0.516

APEH

0.490

SBF1

0.480

SBF2

0.480

Your Current Organism:

Sarcophilus harrisii

NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APEH	FGD4	ENSSHAP00000020664	ENSSHAP00000001465	Acylaminoacyl-peptide hydrolase.	Uncharacterized protein.	0.490
CDC42	FGD1	ENSSHAP00000019325	ENSSHAP00000005345	Cell division cycle 42.	FYVE, RhoGEF and PH domain containing 1.	0.970
CDC42	FGD3	ENSSHAP00000019325	ENSSHAP00000020104	Cell division cycle 42.	Uncharacterized protein.	0.957
CDC42	FGD4	ENSSHAP00000019325	ENSSHAP00000001465	Cell division cycle 42.	Uncharacterized protein.	0.875
CDC42	GNG12	ENSSHAP00000019325	ENSSHAP00000002683	Cell division cycle 42.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.511
ESAM	FGD4	ENSSHAP00000017874	ENSSHAP00000001465	Endothelial cell adhesion molecule.	Uncharacterized protein.	0.558
FGD1	CDC42	ENSSHAP00000005345	ENSSHAP00000019325	FYVE, RhoGEF and PH domain containing 1.	Cell division cycle 42.	0.970
FGD1	FGD3	ENSSHAP00000005345	ENSSHAP00000020104	FYVE, RhoGEF and PH domain containing 1.	Uncharacterized protein.	0.879
FGD1	FGD4	ENSSHAP00000005345	ENSSHAP00000001465	FYVE, RhoGEF and PH domain containing 1.	Uncharacterized protein.	0.516
FGD1	GNG12	ENSSHAP00000005345	ENSSHAP00000002683	FYVE, RhoGEF and PH domain containing 1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.893
FGD3	CDC42	ENSSHAP00000020104	ENSSHAP00000019325	Uncharacterized protein.	Cell division cycle 42.	0.957
FGD3	FGD1	ENSSHAP00000020104	ENSSHAP00000005345	Uncharacterized protein.	FYVE, RhoGEF and PH domain containing 1.	0.879
FGD3	FGD4	ENSSHAP00000020104	ENSSHAP00000001465	Uncharacterized protein.	Uncharacterized protein.	0.733
FGD3	GNG12	ENSSHAP00000020104	ENSSHAP00000002683	Uncharacterized protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.885
FGD4	APEH	ENSSHAP00000001465	ENSSHAP00000020664	Uncharacterized protein.	Acylaminoacyl-peptide hydrolase.	0.490
FGD4	CDC42	ENSSHAP00000001465	ENSSHAP00000019325	Uncharacterized protein.	Cell division cycle 42.	0.875
FGD4	ESAM	ENSSHAP00000001465	ENSSHAP00000017874	Uncharacterized protein.	Endothelial cell adhesion molecule.	0.558
FGD4	FGD1	ENSSHAP00000001465	ENSSHAP00000005345	Uncharacterized protein.	FYVE, RhoGEF and PH domain containing 1.	0.516
FGD4	FGD3	ENSSHAP00000001465	ENSSHAP00000020104	Uncharacterized protein.	Uncharacterized protein.	0.733
FGD4	GNG12	ENSSHAP00000001465	ENSSHAP00000002683	Uncharacterized protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.596