Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TMPRSS12Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (287 aa)    
Predicted Functional Partners:
G3VNK6_SARHA
Uncharacterized protein.
    
 
 0.623
KLC3
Kinesin light chain 3.
    
 
 0.575
AGFG1
ArfGAP with FG repeats 1.
      
 0.561
BCCIP
BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.
      
 0.558
TMPRSS4
Transmembrane serine protease 4; Belongs to the peptidase S1 family.
   
 0.493
PGAM2
Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
    
 
 0.434
G3VQC9_SARHA
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
   
0.418
ST14
Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family.
   
 
  0.408
LOC100934375
Peptidase S1 domain-containing protein.
      
 0.406
LOC100932292
Uncharacterized protein.
      
 0.406
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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