Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (234 aa)    
Predicted Functional Partners:
CSNK2A2
Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily.
   
 0.986
CSNK2A1
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.986
PCGF5
Polycomb group ring finger 5.
    
 0.951
PCGF3
Polycomb group ring finger 3.
    
 0.948
NFKBIA
ANK_REP_REGION domain-containing protein.
    
  0.942
SSRP1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
  0.932
RNF2
Ring finger protein 2.
    
 0.925
CTNNB1
Catenin beta 1.
   
 0.910
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
    
  0.905
DVL2
Dishevelled segment polarity protein 2.
    
 0.904
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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