Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BEST4Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (420 aa)    
Predicted Functional Partners:
RPE65
Retinoid isomerohydrolase RPE65.
      
 0.743
TTR
Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
      
 0.556
CA7
Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family.
   
  
 0.541
OTOP2
Otopetrin 2.
   
  
 0.535
MERTK
Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.
      
 0.447
LOC100930718
Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family.
    
 
 0.441
G3W9S0_SARHA
Uncharacterized protein.
      
 0.433
GUCA2B
Uncharacterized protein.
      
 0.417
RLBP1
Retinaldehyde binding protein 1.
   
  
 0.401
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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