STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRICKLE1Prickle planar cell polarity protein 1. (826 aa)    
Predicted Functional Partners:
VANGL2
Vang-like protein.
    
 0.980
DVL3
Uncharacterized protein.
    
 0.977
VANGL1
Vang-like protein.
    
 0.971
DVL2
Dishevelled segment polarity protein 2.
    
 0.961
PRICKLE2
Prickle planar cell polarity protein 2.
    
 
0.906
PRICKLE3
Uncharacterized protein.
     
 
0.900
FZD3
Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.610
FZD6
Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.
  
 
 0.567
CELSR1
Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.
   
 0.566
SMURF2
SMAD specific E3 ubiquitin protein ligase 2.
    
 0.556
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.