Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
G3VFP8_SARHATNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (245 aa)    
Predicted Functional Partners:
TNFRSF9
TNFR-Cys domain-containing protein.
    
 0.994
CD70
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
  
  
 0.777
TNFSF4
Uncharacterized protein.
  
   
 0.681
CD80
Uncharacterized protein.
  
   
 0.662
LOC100929908
Uncharacterized protein.
  
   
 0.570
TNFSF14
TNF superfamily member 14.
      
 0.535
IL2
Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.
      
 0.474
CD276
Uncharacterized protein.
      
 0.474
MEPE
Uncharacterized protein.
  
     0.461
TNFSF8
TNF superfamily member 8; Belongs to the tumor necrosis factor family.
    
 
 0.455
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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