STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC106Coiled-coil domain containing 106. (281 aa)    
Predicted Functional Partners:
RSPRY1
Ring finger and SPRY domain containing 1.
      
 0.723
GTF3C1
General transcription factor IIIC subunit 1.
      
 0.693
ATF4
Activating transcription factor 4.
    
   0.688
NUDT13
Nudix hydrolase 13.
      
 0.665
RCBTB1
RCC1 and BTB domain containing protein 1.
      
 0.664
ZC3H15
Zinc finger CCCH-type containing 15.
      
 0.654
SNX15
Sorting nexin 15.
      
 0.646
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 
 0.619
CCDC34
Uncharacterized protein.
      
 0.587
G3VBZ7_SARHA
Uncharacterized protein.
      
 0.577
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.