Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRIB2Protein kinase domain-containing protein. (219 aa)    
Predicted Functional Partners:
COP1
WD_REPEATS_REGION domain-containing protein.
    
 
 0.875
STK40
Serine/threonine kinase 40.
    
 
 0.837
TRIB1
Tribbles pseudokinase 1.
    
   0.835
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
 
 0.794
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 0.789
LOC100925927
Uncharacterized protein.
   
 
 0.782
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
 0.778
RIBC2
Uncharacterized protein.
   
 0.739
CREBRF
CREB3 regulatory factor.
    
 0.683
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.681
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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