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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RTN3Reticulon. (959 aa)    
Predicted Functional Partners:
RTN4
Reticulon.
    
0.960
BACE1
Beta-secretase 1; Belongs to the peptidase A1 family.
   
 0.958
BACE2
Beta-secretase 2; Belongs to the peptidase A1 family.
   
 0.937
ATL3
Atlastin GTPase 3.
    
 
 0.638
SEC63
SEC63 homolog, protein translocation regulator.
    
 
 0.594
ATL1
Atlastin GTPase 1.
    
 
 0.536
REEP6
Receptor expression-enhancing protein.
    
 
 0.525
REEP5
Receptor expression-enhancing protein.
   
 
 0.522
ATL2
Atlastin GTPase 2.
    
 
 0.514
VTA1
Vesicle trafficking 1.
    
   0.463
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.