FDX1 protein (Sarcophilus harrisii) - STRING interaction network

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FDX1

2Fe-2S ferredoxin-type domain-containing protein. (188 aa)

Predicted Functional Partners:

FDXR

0.985

G3WAT2_SARHA

0.927

NFS1

0.907

FADS6

0.843

NDUFAB1

0.808

LIAS

0.783

DLAT

0.780

SCLY

0.765

G3W116_SARHA

0.753

CYP11A1

0.753

Your Current Organism:

Sarcophilus harrisii

NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYP11A1	FADS6	ENSSHAP00000015660	ENSSHAP00000022220	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Fatty acid desaturase 6.	0.603
CYP11A1	FDX1	ENSSHAP00000015660	ENSSHAP00000003003	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	2Fe-2S ferredoxin-type domain-containing protein.	0.753
CYP11A1	FDXR	ENSSHAP00000015660	ENSSHAP00000022233	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	NADPH:adrenodoxin oxidoreductase, mitochondrial.	0.712
DLAT	FDX1	ENSSHAP00000015038	ENSSHAP00000003003	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	2Fe-2S ferredoxin-type domain-containing protein.	0.780
DLAT	LIAS	ENSSHAP00000015038	ENSSHAP00000004438	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	0.839
DLAT	NDUFAB1	ENSSHAP00000015038	ENSSHAP00000010826	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.760
FADS6	CYP11A1	ENSSHAP00000022220	ENSSHAP00000015660	Fatty acid desaturase 6.	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	0.603
FADS6	FDX1	ENSSHAP00000022220	ENSSHAP00000003003	Fatty acid desaturase 6.	2Fe-2S ferredoxin-type domain-containing protein.	0.843
FADS6	G3W116_SARHA	ENSSHAP00000022220	ENSSHAP00000009121	Fatty acid desaturase 6.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.603
FADS6	NFS1	ENSSHAP00000022220	ENSSHAP00000021970	Fatty acid desaturase 6.	Aminotran_5 domain-containing protein.	0.474
FDX1	CYP11A1	ENSSHAP00000003003	ENSSHAP00000015660	2Fe-2S ferredoxin-type domain-containing protein.	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	0.753
FDX1	DLAT	ENSSHAP00000003003	ENSSHAP00000015038	2Fe-2S ferredoxin-type domain-containing protein.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.780
FDX1	FADS6	ENSSHAP00000003003	ENSSHAP00000022220	2Fe-2S ferredoxin-type domain-containing protein.	Fatty acid desaturase 6.	0.843
FDX1	FDXR	ENSSHAP00000003003	ENSSHAP00000022233	2Fe-2S ferredoxin-type domain-containing protein.	NADPH:adrenodoxin oxidoreductase, mitochondrial.	0.985
FDX1	G3W116_SARHA	ENSSHAP00000003003	ENSSHAP00000009121	2Fe-2S ferredoxin-type domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.753
FDX1	G3WAT2_SARHA	ENSSHAP00000003003	ENSSHAP00000012537	2Fe-2S ferredoxin-type domain-containing protein.	NifU_N domain-containing protein.	0.927
FDX1	LIAS	ENSSHAP00000003003	ENSSHAP00000004438	2Fe-2S ferredoxin-type domain-containing protein.	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	0.783
FDX1	NDUFAB1	ENSSHAP00000003003	ENSSHAP00000010826	2Fe-2S ferredoxin-type domain-containing protein.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.808
FDX1	NFS1	ENSSHAP00000003003	ENSSHAP00000021970	2Fe-2S ferredoxin-type domain-containing protein.	Aminotran_5 domain-containing protein.	0.907
FDX1	SCLY	ENSSHAP00000003003	ENSSHAP00000005839	2Fe-2S ferredoxin-type domain-containing protein.	Selenocysteine lyase.	0.765