STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGF2Insulin like growth factor 2. (184 aa)    
Predicted Functional Partners:
IGF1R
Tyrosine-protein kinase receptor.
    
 0.987
GPC3
Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
   
 
 0.955
IGF2R
Insulin like growth factor 2 receptor.
    
 
 0.954
IGF1
Insulin like growth factor 1.
     
 
0.914
INSR
Fibronectin type-III domain-containing protein.
    
 0.884
G3WQ31_SARHA
Recep_L_domain domain-containing protein.
    
 0.875
IGFBP6
Insulin like growth factor binding protein 6.
   
 0.872
IGFBP2
Thyroglobulin type-1 domain-containing protein.
   
 0.863
G3W0M2_SARHA
Tyrosine-protein kinase receptor.
    
 0.861
IGFBP5
Insulin like growth factor binding protein 5.
   
 0.844
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.