Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DLGAP5Uncharacterized protein. (625 aa)    
Predicted Functional Partners:
CEP55
Centrosomal protein 55.
   
  
 0.988
HMMR
Hyaluronan mediated motility receptor.
   
 0.985
KIF11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.972
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
  
 0.967
AURKA
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 
 0.965
G3WWX9_SARHA
Uncharacterized protein.
   
  
 0.964
BIRC5
Baculoviral IAP repeat containing 5.
   
  
 0.960
TOP2A
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
   
  
 0.954
TPX2
TPX2 microtubule nucleation factor.
   
  
 0.954
CENPE
Centromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.953
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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