STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)    
Predicted Functional Partners:
TNFRSF1B
Uncharacterized protein.
    
 0.969
LTB
Lymphotoxin beta; Belongs to the tumor necrosis factor family.
   
0.923
LTA
Lymphotoxin alpha; Belongs to the tumor necrosis factor family.
  
  
 
0.906
NFKB1
Nuclear factor kappa B subunit 1.
     
  0.900
TNFRSF25
TNFR-Cys domain-containing protein.
    
 0.529
PLEKHG5
Pleckstrin homology and RhoGEF domain containing G5.
    
 0.529
PLEKHG6
Pleckstrin homology and RhoGEF domain containing G6.
    
 0.529
G3WMH3_SARHA
Uncharacterized protein.
    
 0.529
CD40LG
CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
   
 
 0.496
TNFSF11
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
   
 
 0.466
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
Server load: low (40%) [HD]