STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (450 aa)    
Predicted Functional Partners:
PPP2R1A
Protein phosphatase 2 scaffold subunit Aalpha.
   
 0.944
PPP2R1B
Protein phosphatase 2 scaffold subunit Abeta.
   
 0.944
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.941
PPP2CA
Serine/threonine-protein phosphatase.
   
 0.937
G3X039_SARHA
Serine/threonine-protein phosphatase.
   
 0.937
BCL2
BCL2 apoptosis regulator.
    
 0.911
REC8
REC8 meiotic recombination protein.
   
 0.906
RYR2
Uncharacterized protein.
     
 0.904
PPP1R1A
Protein phosphatase 1 regulatory inhibitor subunit 1A.
     
 0.904
DRD2
Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.
     
 0.902
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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