STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCKTyrosine-protein kinase. (509 aa)    
Predicted Functional Partners:
ZAP70
Zeta chain of T cell receptor associated protein kinase 70.
   
0.980
PTPRC
Uncharacterized protein.
   
 0.975
CD4
Uncharacterized protein.
   
 0.971
CBLB
Cbl proto-oncogene B.
    
 0.953
FYN
Tyrosine-protein kinase.
  
0.949
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.933
CD8B
Ig-like domain-containing protein.
   
 
 0.923
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.917
SYK
Tyrosine-protein kinase.
   
0.740
CD247
CD247 molecule.
   
 0.732
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.