Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but at higher resolution
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HIF1A | SIRT1 | ENSSHAP00000014188 | ENSSHAP00000014878 | Hypoxia inducible factor 1 subunit alpha. | Sirtuin 1. | 0.521 |
HIF1A | SIRT6 | ENSSHAP00000014188 | ENSSHAP00000011597 | Hypoxia inducible factor 1 subunit alpha. | Sirtuin 6. | 0.952 |
NADK | NADSYN1 | ENSSHAP00000013838 | ENSSHAP00000008619 | Uncharacterized protein. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.953 |
NADK | NMNAT1 | ENSSHAP00000013838 | ENSSHAP00000012020 | Uncharacterized protein. | Nicotinamide-nucleotide adenylyltransferase. | 0.934 |
NADK | NMNAT2 | ENSSHAP00000013838 | ENSSHAP00000013771 | Uncharacterized protein. | Nicotinamide nucleotide adenylyltransferase 2. | 0.940 |
NADK | SIRT1 | ENSSHAP00000013838 | ENSSHAP00000014878 | Uncharacterized protein. | Sirtuin 1. | 0.924 |
NADK | SIRT3 | ENSSHAP00000013838 | ENSSHAP00000010518 | Uncharacterized protein. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.920 |
NADK | SIRT4 | ENSSHAP00000013838 | ENSSHAP00000008646 | Uncharacterized protein. | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] | 0.920 |
NADK | SIRT5 | ENSSHAP00000013838 | ENSSHAP00000005803 | Uncharacterized protein. | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] | 0.923 |
NADK | SIRT6 | ENSSHAP00000013838 | ENSSHAP00000011597 | Uncharacterized protein. | Sirtuin 6. | 0.920 |
NADSYN1 | NADK | ENSSHAP00000008619 | ENSSHAP00000013838 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | Uncharacterized protein. | 0.953 |
NADSYN1 | NMNAT1 | ENSSHAP00000008619 | ENSSHAP00000012020 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | Nicotinamide-nucleotide adenylyltransferase. | 0.980 |
NADSYN1 | NMNAT2 | ENSSHAP00000008619 | ENSSHAP00000013771 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | Nicotinamide nucleotide adenylyltransferase 2. | 0.974 |
NADSYN1 | SIRT1 | ENSSHAP00000008619 | ENSSHAP00000014878 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | Sirtuin 1. | 0.950 |
NADSYN1 | SIRT3 | ENSSHAP00000008619 | ENSSHAP00000010518 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.937 |
NADSYN1 | SIRT4 | ENSSHAP00000008619 | ENSSHAP00000008646 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] | 0.937 |
NADSYN1 | SIRT5 | ENSSHAP00000008619 | ENSSHAP00000005803 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] | 0.939 |
NADSYN1 | SIRT6 | ENSSHAP00000008619 | ENSSHAP00000011597 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | Sirtuin 6. | 0.937 |
NAMPT | NMNAT1 | ENSSHAP00000016134 | ENSSHAP00000012020 | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. | Nicotinamide-nucleotide adenylyltransferase. | 0.942 |
NAMPT | NMNAT2 | ENSSHAP00000016134 | ENSSHAP00000013771 | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. | Nicotinamide nucleotide adenylyltransferase 2. | 0.934 |
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